Effectiveness of antidepressants in improving the prognosis of COVID-19: A systematic review and meta-analysis.

ABSTRACT:

Objective, and material and methods

A systematic review and meta-analysis was performed to evaluate the effectiveness of antidepressants in reducing the poor evolution of COVID-19 disease (a composite variable including death, hospitalization and need for mechanical ventilation), and mortality, according the guidelines for Systematic Reviews of Interventions published by the Cochrane library.

Source of data

MEDLINE, EMBASE and COCHRANE LIBRARY were consulted up to February 25, 2022. Unpublished studies were searched on clinicaltrials.gov platform.

Selection of studies

Seven masked and unmasked, observational and experimental studies evaluating death, hospitalization and need for mechanical ventilation were selected. A second subgroup analysis with mortality variable w

SUBMITTER: Cobos-Campos R 

PROVIDER: S-EPMC10696393 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature