Association between human herpesvirus infection and cervical carcinoma: a systematic review and meta-analysis.

ABSTRACT:

Background

Cervical cancer (CC) is one of the most common gynecologic tumors among women around the world. Although the etiological role of human papillomavirus (HPV) in CC is well established, other factors in CC carcinogenesis remains unclear. Here, we performed a systematic review and meta-analysis to explore the association between infections of human herpesvirus (HHVs) and CC risk.

Methods

Embase and PubMed databases were utilized to search the relevant studies. The revised JBI Critical Appraisal Tool was used to assess the quality of the included studies. Prevalence and odds ratios (ORs) with 95% confidence intervals (CI) were calculated to evaluate the association between viral infection and CC or precancerous cervical lesions (PCL).

Results

Totally 67 eligible

SUBMITTER: Zhang H 

PROVIDER: S-EPMC10696706 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature