Unknown

Dataset Information

0

Hybrid AuNPs-3MPS-MTX nanosystem and its evaluation for treating cervical cancer and melanoma.

ABSTRACT: This research presents an evaluation of a hybrid material based on gold nanoparticles (AuNPs), stabilized with the thiol 3-mercapto-propanesulfonate (3MPS) and loaded with the methotrexate drug (MTX). The AuNPs-3MPS-MTX nanosystem was tested for the treatment of cervical cancer and melanoma, using the B16-F10 melanoma and HeLa cell lines. The tests performed on cell cultures assessed the efficiency of the studied nanosystem on tumor cells, as well as its toxicology.

SUBMITTER: Hernandez-Esparza MJ 

PROVIDER: S-EPMC10696946 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Hybrid AuNPs-3MPS-MTX nanosystem and its evaluation for treating cervical cancer and melanoma.

Hernández-Esparza M J MJ   Fratoddi Ilaria I   Cerra Sara S   Juarez-Moreno K K   Huirache-Acuña R R  

Nanoscale advances 20231117 24

This research presents an evaluation of a hybrid material based on gold nanoparticles (AuNPs), stabilized with the thiol 3-mercapto-propanesulfonate (3MPS) and loaded with the methotrexate drug (MTX). The AuNPs-3MPS-MTX nanosystem was tested for the treatment of cervical cancer and melanoma, using the B16-F10 melanoma and HeLa cell lines. The tests performed on cell cultures assessed the efficiency of the studied nanosystem on tumor cells, as well as its toxicology. ...[more]

Similar Datasets

Unknown Theranostic nanobubble encapsulating a plasmon-enhanced upconversion hybrid nanosystem for cancer therapy.
| S-EPMC6929987 | biostudies-literature
Unknown A lipo-polymeric hybrid nanosystem with metal enhanced fluorescence for targeted imaging of metastatic breast cancer
| S-EPMC10911974 | biostudies-literature
Unknown Peptide-biphenyl hybrid-capped AuNPs: stability and biocompatibility under cell culture conditions.
| S-EPMC3716793 | biostudies-literature
Transcriptomics Evaluation of the Mammalian Aquaporin Inhibitors Auphen and Z433927330 in Treating Breast Cancer
2024-08-01 | GSE271926 | GEO
Unknown An Anisotropic Gold-Palladium Heterostructured Nanosystem for Synergistically Overcoming Radioresistance and Enhancing Melanoma Radioimmunotherapy.
| S-EPMC12376628 | biostudies-literature
Unknown Prodrug nanosystem equipped with a sonosensitizer for combined chemotherapy and sonodynamic therapy of melanoma.
| S-EPMC12433508 | biostudies-literature
Genomics Cervical cancer
| PRJNA144107 | ENA
Unknown Hybrid layer-by-layer assembly of AuNPs/NSF composite for electrochemical detection of miRNA-196a.
| S-EPMC11599500 | biostudies-literature
Unknown Dissolving Microneedles with Spatiotemporally controlled pulsatile release Nanosystem for Synergistic Chemo-photothermal Therapy of Melanoma.
| S-EPMC7381723 | biostudies-literature
Unknown A Spatiotemporally Controlled Gene-Regulation Strategy for Combined Tumor Therapy Based on Upconversion Hybrid Nanosystem.
| S-EPMC11515897 | biostudies-literature