Antibiotic treatment durations for pyogenic liver abscesses: A systematic review.

ABSTRACT:

Background

We sought to systematically review the existing research on pyogenic liver abscesses to determine what data exist on antibiotic treatment durations.

Methods

We conducted a systematic review and meta-analysis of contemporary medical literature from 2000 to 2020, searching for studies of pyogenic liver abscesses. The primary outcome of interest was mean antibiotic treatment duration, which we pooled by random-effects meta-analysis. Meta-regression was performed to examine characteristics influencing antibiotic durations.

Results

Sixteen studies (of 3,933 patients) provided sufficient data on antibiotic durations for pooling in meta-analysis. Mean antibiotic durations were highly variable across studies, from 8.4 (SD 5.3) to 68.9 (SD 30.3) days. The pooled mea

SUBMITTER: Curran J 

PROVIDER: S-EPMC10697100 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature