Application of Skyline software for detecting prohibited substances in doping control analysis.

ABSTRACT: As the number of prohibited drugs has been progressively increasing and analytical methods for detecting such substances are renewed continuously for doping control, the need for more sensitive and accurate doping analysis has increased. To address the urgent need for high throughput and accurate analysis, liquid chromatography with tandem mass spectrometry is actively utilized in case of most of the newly designated prohibited substances. However, because all mass spectrometer vendors provide data processing software that is incapable of handling other instrumental data, it is difficult to cover all doping analysis procedures, from method development to result reporting, on one platform. Skyline is an open-source and vendor-neutral software program invented for the method development and

SUBMITTER: Lee HJ 

PROVIDER: S-EPMC10697575 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature