Age-specific and sex-specific risks for HCC in African-born persons with chronic hepatitis B without cirrhosis.

ABSTRACT:

Background

The international recommendations of HCC surveillance for African-born persons with chronic hepatitis B (CHB) without cirrhosis are divergent, probably due to scarce data on incidence rate (IR) for HCC.

Methods

We assembled a cohort with prospectively collected data of Swedish residents of African origin with diagnosed CHB without cirrhosis at baseline from 1990 to 2015. Data from nationwide registers were used to calculate the sex-specific IR and IR ratio (incidence rate ratios) in relation to age, comorbidities, and birth region, using a generalized linear model with a log-link function and Poisson distribution.

Results

Among 3865 African-born persons with CHB without cirrhosis at baseline, 31 (0.8%; 77.4% men) developed HCC during a median of 11.1 years

SUBMITTER: Kamal H 

PROVIDER: S-EPMC10697596 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature