Relationship of retinal capillary plexus and ganglion cell complex with mild cognitive impairment and dementia.

ABSTRACT:

Objective

To investigate relationship of the retinal capillary plexus (RCP) and ganglion cell complex (GCC) with mild cognitive impairment (MCI) and dementia in a community-based study1.

Methods

This cross-sectional study incorporated the participants of the Jidong Eye Cohort Study. Optical coherence tomography angiography was performed to obtain RCP vessel density and GCC thickness with detailed segments. The Mini-mental State Examination and Montreal Cognitive Assessment were used to assess cognitive status by professional neuropsychologists. Participants were thus divided into three groups: normal, mild cognitive impairment, and dementia. Multivariable analysis was used to measure relationship of ocular parameters with cognitive impairment.

Results

Of the 2678 part

SUBMITTER: Li C 

PROVIDER: S-EPMC10698172 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature