Association of OCT and OCT angiography measures with the development and worsening of diabetic retinopathy in type 2 diabetes.

ABSTRACT:

Objective

To assess if optical coherence tomography (OCT) and OCT angiography (OCTA) measures are associated with the development and worsening of diabetic retinopathy (DR) over four years.

Methods

280 participants with type 2 diabetes underwent ultra-wide field fundus photography, OCT and OCTA. OCT-derived macular thickness measures, retinal nerve fibre layer and ganglion cell-inner plexiform layer thickness and OCTA-derived foveal avascular zone area, perimeter, circularity, vessel density (VD) and macular perfusion (MP) were examined in relation to the development and worsening of DR over four years.

Results

After four years, 206 eyes of 219 participants were eligible for analysis. 27 of the 161 eyes (16.7%) with no DR at baseline developed new DR, which was associ

SUBMITTER: Srinivasan S 

PROVIDER: S-EPMC10698183 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature