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Effects of RNA methylation on Tumor angiogenesis and cancer progression.


ABSTRACT: Tumor angiogenesis plays vital roles in the growth and metastasis of cancer. RNA methylation is one of the most common modifications and is widely observed in eukaryotes and prokaryotes. Accumulating studies have revealed that RNA methylation affects the occurrence and development of various tumors. In recent years, RNA methylation has been shown to play an important role in regulating tumor angiogenesis. In this review, we mainly elucidate the mechanisms and functions of RNA methylation on angiogenesis and progression in several cancers. We then shed light on the role of RNA methylation-associated factors and pathways in tumor angiogenesis. Finally, we describe the role of RNA methylation as potential biomarker and novel therapeutic target.

SUBMITTER: Han M 

PROVIDER: S-EPMC10698974 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature

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Effects of RNA methylation on Tumor angiogenesis and cancer progression.

Han Mingyu M   Sun Haifeng H   Zhou Quanbo Q   Liu Jinbo J   Hu Junhong J   Yuan Weitang W   Sun Zhenqiang Z  

Molecular cancer 20231206 1


Tumor angiogenesis plays vital roles in the growth and metastasis of cancer. RNA methylation is one of the most common modifications and is widely observed in eukaryotes and prokaryotes. Accumulating studies have revealed that RNA methylation affects the occurrence and development of various tumors. In recent years, RNA methylation has been shown to play an important role in regulating tumor angiogenesis. In this review, we mainly elucidate the mechanisms and functions of RNA methylation on angi  ...[more]

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