Aluminium-based ionic liquid grafted on biochar as a heterogeneous catalyst for the selective synthesis of tetrazole and 2,3-dihydroquinazolin 4(1H)-one derivatives.

ABSTRACT: 2,3-Dihydroquinazolin-4(1H)-one and tetrazole are a class of nitrogen-containing heterocyclic compounds that play an important role in drug design and are an important part of many biological and industrial compounds. In this study, aluminium-based ionic liquid grafted onto a biochar surface (BC/[TESPMI]AlCl₄) was synthesized and used as a catalyst for the synthesis of a series of biological derivatives including 2,3-dihydroquinazolin-4(1H)-ones in ethanol at reflux conditions and tetrazoles in PEG-400 at 110 °C. All products were obtained with good selectivity and yield of 90 to 97%. The catalyst was thoroughly characterized using various techniques such as thermogravimetric analysis (TGA), energy-dispersive X-ray spectroscopy (EDX), and powder X-ray diffraction (

SUBMITTER: Norouzi M 

PROVIDER: S-EPMC10699257 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature