The Forkhead Gene fkhB is Necessary for Proper Development in Aspergillus nidulans.

ABSTRACT: The forkhead domain genes are important for development and morphogenesis in fungi. Six forkhead genes fkhA-fkhF have been found in the genome of the model filamentous Ascomycete Aspergillus nidulans. To identify the fkh gene(s) associated with fungal development, we examined mRNA levels of these six genes and found that the level of fkhB and fkhD mRNA was significantly elevated during asexual development and in conidia. To investigate the roles of FkhB and FkhD, we generated fkhB and fkhD deletion mutants and complemented strains and investigated their phenotypes. The deletion of fkhB, but not fkhD, affected fungal growth and both sexual and asexual development. The fkhB deletion mutant exhibited decreased colony

SUBMITTER: Jang SY 

PROVIDER: S-EPMC10699268 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature