Implementation of an intravenous sotalol initiation protocol: Implications for feasibility, safety, and length of stay.

ABSTRACT:

Introduction

Oral sotalol initiation requires a multiple-day, inpatient admission to monitor for QT prolongation during loading. A 1-day intravenous (IV) sotalol loading protocol was approved by the United States Food and Drug Administration in March 2020, but limited data on clinical use and administration currently exists. This study describes implementation of an IV sotalol protocol within an integrated health system, provides initial efficacy and safety outcomes, and examines length of stay (LOS) compared with oral sotalol initiation.

Methods

IV sotalol was administered according to a prespecified initiation protocol to adult patients with refractory atrial or ventricular arrhythmias. Baseline characteristics, safety and feasibility outcomes, and LOS were compared with p

SUBMITTER: Liu AY 

PROVIDER: S-EPMC10699543 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature