Antibiofilm activity of biosynthesized silver and copper nanoparticles using Streptomyces S29.

ABSTRACT: Microbial resistance and biofilm formation have been considered as the main problems associated with microbial resistance. Several antimicrobial agents cannot penetrate biofilm layers and cannot eradicate microbial infection. Therefore, the aim of this study is the biological synthesis of silver and copper nanoparticles to assess their activities on bacterial attachment and on the viability of dormant cells within the biofilm matrix. Ag-NPs and Cu-NPs were biosynthesized using Streptomyces isolate S29. The biologically synthesized Ag-NPs and Cu-NPs exhibited brown and blue colors and were detected by UV/Vis spectrophotometry at 476 and 594 nm, respectively. The Ag-NPs showed an average size of 10-20 nm as indicated by TEM, and 25-35 nm for Cu-NPs. Both Ag-NPs and Cu-NPs were monodispersed

SUBMITTER: Elshaer S 

PROVIDER: S-EPMC10700280 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature