Cross-sectional analysis of the correlation between serum uric acid and trabecular bone score: NHANES 2005-2008.

ABSTRACT: Serum uric acid (SUA) has been discovered to be associated with bone mineral density (BMD), but its relationship with trabecular bone score (TBS) remains unclear. Thus, the aim of our study was to investigate the association between SUA levels and TBS. Our study included 5895 individuals over 20 years old (3061 men and 2834 women) from NHANES 2005-2008. To analyze the association between SUA and TBS, multivariate linear regression models with covariate adjustments were applied. Furthermore, population description, stratified analysis, single factor analysis, smooth curve fitting, interaction analysis, and threshold effect and saturation effect analysis were also conducted. After adjusting for covariates, SUA showed a strong negative relationship with total TBS (β = 0.319; 95% CI 0.145-0.49

SUBMITTER: Li Y 

PROVIDER: S-EPMC10700542 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature