Disentangling sensory precision and prior expectation of change in autism during tactile discrimination.

ABSTRACT: Predictive coding theories suggest that core symptoms in autism spectrum disorders (ASD) may stem from atypical mechanisms of perceptual inference (i.e., inferring the hidden causes of sensations). Specifically, there would be an imbalance in the precision or weight ascribed to sensory inputs relative to prior expectations. Using three tactile behavioral tasks and computational modeling, we specifically targeted the implicit dynamics of sensory adaptation and perceptual learning in ASD. Participants were neurotypical and autistic adults without intellectual disability. In Experiment I, tactile detection thresholds and adaptation effects were measured to assess sensory precision. Experiments II and III relied on two-alternative forced choice tasks designed to elicit a time-order effect, whe

SUBMITTER: Sapey-Triomphe LA 

PROVIDER: S-EPMC10700558 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature