Childhood socioeconomic position and sex-specific trajectories of metabolic traits across early life: prospective cohort study.

ABSTRACT:

Background

Socioeconomic inequalities in cardiovascular disease risk begin early in life and are more pronounced in females than males later in life. Causal atherogenic traits explaining this are not well understood. We explored sex-specific associations between childhood socioeconomic position (SEP) and molecular measures of systemic metabolism across early life.

Methods

Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC), a population-based birth cohort in southwest England. Pregnant women with an expected delivery date between 1991 and 1992 were invited to participate. Maternal education was the primary indicator of SEP. Concentrations of 148 metabolic traits from targeted metabolomics (nuclear magnetic resonance spectroscopy) from research clinics

SUBMITTER: O'Neill KN 

PROVIDER: S-EPMC10700592 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature