Topological properties and connectivity patterns in brain networks of patients with refractory epilepsy combined with intracranial electrical stimulation.

ABSTRACT:

Objective

Although intracranial electrical stimulation has emerged as a treatment option for various diseases, its impact on the properties of brain networks remains challenging due to its invasive nature. The combination of intracranial electrical stimulation and whole-brain functional magnetic resonance imaging (fMRI) in patients with refractory epilepsy (RE) makes it possible to study the network properties associated with electrical stimulation. Thus, our study aimed to investigate the brain network characteristics of RE patients with concurrent electrical stimulation and obtain possible clinical biomarkers.

Methods

Our study used the GRETNA toolbox, a graph theoretical network analysis toolbox for imaging connectomics, to calculate and analyze the network topological at

SUBMITTER: Sun Y 

PROVIDER: S-EPMC10701286 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature