Effect of lyophilized gelatin-norbornene cryogel size on calvarial bone regeneration.

ABSTRACT: Molding processes with molds containing topographical structures have been used for fabrication of hydrogel and cryogel particles. However, they can involve difficulties in separation of fabricated particles with complex shape from the molds or repeated fabrication of the particles although the overall processes do not require much skill and equipment. In this study, molds with etched superhydrophobic patterns have been developed by etching polytetrafluoroethylene (PTFE) blocks in user-defined designs with a femtosecond (FS) laser-based etching system. Lyophilized cryogel particles with various designs and sizes were fabricated by molding precursors with these PTFE molds. Additionally, the clean and easy separation of particles from the molds allowed repeated fabrication of the particles.

SUBMITTER: Kim B 

PROVIDER: S-EPMC10701364 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature