Impact of loop diuretic dosage in a population of patients with acute heart failure: a retrospective analysis.

ABSTRACT:

Background

Loop diuretics are essential for managing congestion in acute heart failure (AHF) patients, but concerns exist about their dosing and administration. This study aims to explore the relationship between aggressive diuretic treatment and clinical outcomes in AHF patients.

Methods

We randomly selected 370 AHF patients from admissions at Maastricht University Medical Center between January 2011 and March 2017. Patients were divided into four quartiles based on diuretic doses administrated during index hospitalization. The primary endpoint was a composite of cardiovascular (CV) rehospitalization or death at 1 year.

Results

42.4% of patients experimented the primary outcome The composite endpoint rates were 35.4%, 41.6%, 38.5%, and 54.9%, respectively, from lowes

SUBMITTER: Meani P 

PROVIDER: S-EPMC10701382 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature