The Association of Prenatal Vitamin D Status With Pregnancy and Neonatal Outcomes.

ABSTRACT:

Context

Vitamin D inadequacy is globally prevalent among pregnant women; however, its impact on pregnancy remains inconclusive.

Objective

This study aims to explore the associations of maternal and umbilical cord serum 25-hydroxyvitamin D (25(OH)D) levels with pregnancy and neonatal outcomes.

Method

We used archived serum samples from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study participants in the Hong Kong center and assayed maternal 25(OH)D levels at midgestation and umbilical cord 25(OH)D at birth using liquid chromatography-tandem mass spectroscopy. Data regarding pregnancy and perinatal outcomes were extracted from the HAPO study dataset and the hospital computerized medical system.

Results

Only 247 (16.4%) mothers and 66 (5.0%) neonates m

SUBMITTER: Mao D 

PROVIDER: S-EPMC10701472 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature