Isolation, characterization, and immunomodulatory activity evaluation of probiotic strains from colostrum and canine milk.

ABSTRACT:

Background

This study aimed to characterize potential probiotic strains for use in dogs to prevent infectious enteropathies. Lactic acid bacteria (LAB) isolated from canine milk and colostrum were characterized according to their functional properties, including their resistance to gastrointestinal conditions, inhibitory effect against pathogens, and intestinal adhesion.

Methods

The immunomodulatory effects of the strains were also analyzed in in vitro and in vivo studies. Among the strains evaluated, two LAB strains (TUCO-16 and TUCO-17) showed remarkable resistance to pH 3.0, bile salts, and pancreatin, as well as inhibitory effects against pathogenic Escherichia coli, Salmonella sp., and Clostridium perfringens.

Results

The TUCO-16 and T

SUBMITTER: Quilodran-Vega SR 

PROVIDER: S-EPMC10701529 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature