Treatment of Severe Palmoplantar Pustular Psoriasis With Bimekizumab.

ABSTRACT:

Importance

Palmoplantar pustulosis (PPP) and palmoplantar plaque psoriasis with pustules remain challenging to treat. Studies suggest that an interleukin 17 or interleukin 36 loop acts synergistically in these diseases to induce palmoplantar pustules.

Objective

To assess the effectiveness of bimekizumab in treating PPP and palmoplantar plaque psoriasis with pustules.

Design, setting, and participants

This case series involved 21 adults with PPP (11 patients) or palmoplantar plaque psoriasis with pustules (10 patients) treated at 1 of 7 tertiary dermatological centers in France from September 2022 through June 2023. All patients treated with bimekizumab for at least 3 months were included in the analyses.

Main outcomes and measures

The main outcome was the postt

SUBMITTER: Passeron T 

PROVIDER: S-EPMC10701662 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature