Oral Acitretin Plus Topical Triamcinolone vs Topical Triamcinolone Monotherapy in Patients With Symptomatic Oral Lichen Planus: A Randomized Clinical Trial.

ABSTRACT:

Importance

Symptomatic oral lichen planus (OLP) can be challenging to treat.

Objective

To compare the efficacy of oral acitretin plus topical triamcinolone acetonide (TAC), 0.1%, with TAC monotherapy in patients with symptomatic OLP.

Design, setting, and participants

This monocentric, investigator-initiated, placebo-controlled, investigator- and patient-blinded randomized clinical trial was conducted from December 2018 to June 2020 at the Postgraduate Institute of Medical Education and Research, a tertiary referral center in Chandigarh, India. Sixty-four patients 18 years or older with symptomatic OLP were recruited by consecutive sampling. Data were analyzed from July to December 2020.

Intervention

The patients were randomized to receive either a combination o

SUBMITTER: Vinay K 

PROVIDER: S-EPMC10701665 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature