Clinical impact of pre-existing acute exacerbation in patients with interstitial lung disease who underwent lung transplantation.

ABSTRACT:

Background

Acute exacerbation of interstitial lung disease (AE-ILD) significantly impacts prognosis, leading to high mortality rates. Although lung transplantation is a life-saving treatment for selected patients with ILD, its outcomes in those presenting with AE-ILD have yielded conflicting results compared with those with stable ILD. This study aims to investigate the impact of pre-existing AE on the prognosis of ILD patients who underwent lung transplantation.

Method

We conducted a single-center retrospective study by reviewing the medical records of 108 patients who underwent lung transplantation for predisposing ILD at Asan Medical Center, Seoul, South Korea, between 2008 and 2022. The primary objective was to compare the survival of patients with AE-ILD at the time of

SUBMITTER: Kim HH 

PROVIDER: S-EPMC10701919 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature