Association of periodontitis and tooth loss with extent of coronary atherosclerosis in patients with type 2 diabetes mellitus.

ABSTRACT:

Aim

The objective was to investigate the association of periodontitis and tooth loss with extent of diabetic coronary atherosclerosis.

Materials and methods

272 patients who were hospitalized at Shanghai East hospital and underwent a coronary artery calcium (CAC) CT scan were enrolled in this study. Individuals were grouped based on their CAC scores into a normal-to-mild coronary atherosclerosis (AS) group (0 ≤ score ≤ 100, n=184) and a moderate-to-severe group (score≥101, n=88). Periodontitis parameters and number of missing teeth were evaluated for every patient. The severity of periodontitis was categorized as mild, moderate, or severe. The taxonomic composition of the microbiota was determined using full-length 16S ribosomal RNA gene sequencing. Salivary inflammatory fac

SUBMITTER: Shen M 

PROVIDER: S-EPMC10702216 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature