Prevalence and treatment of panic disorder in bipolar disorder: systematic review and meta-analysis.

ABSTRACT:

Question

Recent data suggest that anxiety disorders are as often comorbid with bipolar disorder (BD) as with unipolar depression. The literature on panic disorder (PD) comorbid with BD has been systematically reviewed and subject to meta-analysis.

Study selection and analysis

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were thoroughly followed for literature search, selection and reporting of available evidence. The variance-stabilising Freeman-Tukey double arcsine transformation was used in the meta-analysis of prevalence estimates. Both fixed-effect and random-effects models with inverse variance method were applied to estimate summary effects for all combined studies. Heterogeneity was assessed and measured with Cochran's Q and I

SUBMITTER: Preti A 

PROVIDER: S-EPMC10702268 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature