Timing of exercise therapy when initiating adjuvant chemotherapy for breast cancer: a randomized trial.

ABSTRACT:

Aims

The most appropriate timing of exercise therapy to improve cardiorespiratory fitness (CRF) among patients initiating chemotherapy is not known. The effects of exercise therapy administered during, following, or during and following chemotherapy were examined in patients with breast cancer.

Methods and results

Using a parallel-group randomized trial design, 158 inactive women with breast cancer initiating (neo)adjuvant chemotherapy were allocated to receive (1:1 ratio): usual care or one of three exercise regimens-concurrent (during chemotherapy only), sequential (after chemotherapy only), or concurrent and sequential (continuous) (n = 39/40 per group). Exercise consisted of treadmill walking three sessions/week, 20-50 min at 55%-100% of peak oxygen consumption (VO2peak)

SUBMITTER: Scott JM 

PROVIDER: S-EPMC10702461 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature