Development of a Diagnostic Model for Differentiating Tuberculous Spondylitis and Pyogenic Spondylitis with MRI: A Multicenter Retrospective Observational Study.

ABSTRACT:

Study design

Multicenter retrospective observational study.

Objective

This study aimed to distinguish tuberculous spondylitis (TS) from pyogenic spondylitis (PS), using magnetic resonance imaging (MRI). Further, a novel diagnostic model for differential diagnosis was developed.

Summary of background data

TS and PS are the two most common spinal infections. Distinguishing between these types clinically is challenging. Delayed diagnosis can lead to deficits or kyphosis. Currently, there is a lack of radiology-based diagnostic models for TS and PS.

Methods

We obtained radiological images from MRI imaging of patients with TS and PS and applied least absolute shrinkage and selection operator (LASSO) regression to select the optimal features for a predictive model. P

SUBMITTER: Wang J 

PROVIDER: S-EPMC10702692 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature