Genomic analyses of Burkholderia respiratory isolates indicates two evolutionarily distinct B. anthina clades.

ABSTRACT:

Introduction

The Burkholderia cepacia complex (BCC) encompasses a group of at least 22 genetically distinct gram-negatives bacterial species ubiquitous in nature. Recognised as a group of genetically and phenotypically flexible species, the BCC inhabits diverse ecological niches causing both plant and human diseases. Comparative genomic analysis provides an in depth understanding into the population biology, phylogenetic relationship, and genomic architecture of species.

Methods

Here, we genomically characterise Burkholderia anthina isolated from patients with chronic lung infections, an understudied pathogen within the Burkholderia cepacia complex.

Results

We demonstrate that B. anthina is polyphyletic and constitutes two distinct evolutio

SUBMITTER: Pham A 

PROVIDER: S-EPMC10702961 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature