Real-world national trends and influencing factors preference of non-vitamin K antagonist oral anticoagulants in China.

ABSTRACT:

Backgrounds

Non-vitamin K antagonist oral anticoagulants (NOACs) have been recommended as the first choice over warfarin for non-valvular atrial fibrillation (AF). However, there is limited data about their usage in mainland China.

Methods

Prescriptions of patients diagnosed with AF and containing OACs were extracted from Hospital Prescription Cooperation Project from January 2016 to March 2021. The primary outcome was the changing percentage of different OACs. The secondary outcomes were frequencies as well as factors with the choice of different OACs and dosage of NOACs. Univariate and Multivariate logistic regressions were conducted to explore possible factors. All statistical analyses were performed using SAS software (Version 9.4).

Results

Among the 220,083 disti

SUBMITTER: Zhu S 

PROVIDER: S-EPMC10702983 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature