Neutrophil extracellular traps in upper respiratory tract secretions: insights into infectious and allergic rhinitis.

ABSTRACT:

Introduction

Neutrophil extracellular traps (NETs) are structures released by neutrophils in response to various infections. NETs have a biocidal role and have been demonstrated to be effective against bacteria, fungi, viruses, and parasites. Depending on the situation, NETs can protect the host from pathogen invasion or contribute to the development of autoimmune diseases such as cystic fibrosis and rheumatoid arthritis. In this study, we aimed to investigate the occurrence of NET as one of the components in upper respiratory tract secretions in infectious and allergic diseases.

Methods

Nasal mucus was collected from donors diagnosed with infectious rhinitis or allergic rhinitis. The extracellular DNA content was determined using SytoxGreen staining, and the total protein p

SUBMITTER: Zawrotniak M 

PROVIDER: S-EPMC10702990 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature