Time-dependent association between STOPP and START criteria and gastrointestinal bleeding in older patients using routinely collected primary care data.

ABSTRACT:

Purpose

Only few studies have assessed the preventive effect of the STOPP/START criteria on adverse events. We aim to quantify 1) the association between nonadherence to STOPP/START criteria and gastrointestinal bleedings, and 2) the association between exposure to the potentially harmful START-medications and gastrointestinal bleedings.

Design

A retrospective cohort study using routinely collected data of patients aged ≥ 65 years from the electronic health records (EHR) of 49 general practitioners (GPs) in 6 GP practices, from 2007 to 2014. The database is maintained in the academic research network database (AHA) of Amsterdam UMC, the Netherlands.

Methods

Gastrointestinal bleedings were identified using ICPC codes and free text inspections. Three STOPP and six START

SUBMITTER: Veldhuis A 

PROVIDER: S-EPMC10703206 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature