Exploring the genetic diversity of the Japanese population: Insights from a large-scale whole genome sequencing analysis.

ABSTRACT: The Japanese archipelago is a terminal location for human migration, and the contemporary Japanese people represent a unique population whose genomic diversity has been shaped by multiple migrations from Eurasia. We analyzed the genomic characteristics that define the genetic makeup of the modern Japanese population from a population genetics perspective from the genomic data of 9,287 samples obtained by high-coverage whole-genome sequencing (WGS) by the National Center Biobank Network. The dataset comprised populations from the Ryukyu Islands and other parts of the Japanese archipelago (Hondo). The Hondo population underwent two episodes of population decline during the Jomon period, corresponding to the Late Neolithic, and the Edo period, corresponding to the Early Modern era, while the

SUBMITTER: Kawai Y 

PROVIDER: S-EPMC10703243 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature