An evaluation of Mp1p antigen screening for talaromycosis in HIV-infected antiretroviral therapy-naive population in Guangdong, China.

ABSTRACT:

Background

Talaromycosis is one of the most common opportunistic infections in human immunodeficiency virus (HIV) infected patients. However, few researches have explored the prevalence in Southern China and fully assessed the value of the Mp1p antigen screening for the diagnosis of talaromycosis.

Methodology/principal findings

We performed a cross-sectional study of HIV-infected antiretroviral therapy (ART)-naïve adult patients who were seen in 2018 at Guangzhou Eighth People's Hospital, Guangzhou Medical University. Serum samples collected from all the 784 enrolled patients were tested for Mp1p antigen using double-antibody sandwich enzyme-linked immunosorbent assay. A culture of pathogen was conducted in 350 clinically suspected patients to confirm talaromycosis. The over

SUBMITTER: Gong D 

PROVIDER: S-EPMC10703259 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature