An allele-sharing, moment-based estimator of global, population-specific and population-pair FST under a general model of population structure.

ABSTRACT: Being able to properly quantify genetic differentiation is key to understanding the evolutionary potential of a species. One central parameter in this context is FST, the mean coancestry within populations relative to the mean coancestry between populations. Researchers have been estimating FST globally or between pairs of populations for a long time. More recently, it has been proposed to estimate population-specific FST values, and population-pair mean relative coancestry. Here, we review the several definitions and estimation methods of FST, and stress that they provide values relative to a reference population. We show the good statistical properties of an allele-sharing, method of moments based estimator of FST (global, population-specific and population-pair) under a very general mod

SUBMITTER: Goudet J 

PROVIDER: S-EPMC10703327 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature