Association between increased C-reactive protein and cardiovascular disease among patients with rectal cancer.

ABSTRACT:

Purpose

This study aimed to investigate the association between increased C-reactive protein (CRP) and cardiovascular disease (CVD) in individuals with rectal cancer, as well as to understand the effect of chemotherapy for cancer on increasing CRP and its underlying mechanisms.

Patients and methods

From January 1, 2010 to December 31, 2020, individuals with rectal cancer were evaluated at the First Affiliated Hospital of Gannan Medical University. Then, in patients with rectal cancer, the relationship between increased CRP and CVD attributes was summarized, and the impact of chemotherapy on CRP levels was qualitatively assessed. For further investigation into potential regulatory mechanisms of CRP, differentially expressed genes (DEGs), GO and KEGG enrichment analyses were c

SUBMITTER: Qiao H 

PROVIDER: S-EPMC10703434 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature