ACC neural ensemble dynamics are structured by strategy prevalence.

ABSTRACT: Medial frontal cortical areas are thought to play a critical role in the brain's ability to flexibly deploy strategies that are effective in complex settings, yet the underlying circuit computations remain unclear. Here, by examining neural ensemble activity in male rats that sample different strategies in a self-guided search for latent task structure, we observe robust tracking during strategy execution of a summary statistic for that strategy in recent behavioral history by the anterior cingulate cortex (ACC), especially by an area homologous to primate area 32D. Using the simplest summary statistic - strategy prevalence in the last 20 choices - we find that its encoding in the ACC during strategy execution is wide-scale, independent of reward delivery, and persists through a substantia

SUBMITTER: Proskurin M 

PROVIDER: S-EPMC10703442 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature