Liver transplant selection criteria and outcomes in critically ill patients with ACLF.

ABSTRACT:

Background & aims

Retrospective studies have reported good results with liver transplantation (LTx) for acute-on-chronic liver failure (ACLF) in selected patients. The aim of this study was to evaluate the selection process for LTx in patients with ACLF admitted to the intensive care unit (ICU) and to assess outcomes.

Methods

This prospective, non-interventional, single high-volume center study collected data on patients with ACLF admitted to the ICU between 2017-2020.

Results

Among 200 patients (mean age: 55.0 ± 11.2 years and 74% male), 96 patients (48%) were considered potential candidates for LTx. Unfavourable addictology criteria (n = 76) was the main reason for LTx ineligibility. Overall, 69 patients were listed for LTx (34.5%) and 50 were transplanted (25% of t

SUBMITTER: Sacleux SC 

PROVIDER: S-EPMC10703599 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature