ABSTRACT: For decades, the Buriganga River in Dhaka, Bangladesh, has suffered from persistent pollution, leading to heavy metal contamination in fish samples that poses significant risks to human health. This study conducted an analysis of the whole bodies of various fish species, including Heteropnuestes fossilis, Channa punctatus, Notopterus notopterus Channa striata and Colisa fasciata to examine the concentrations of Chromium, Manganese, Nickel, Copper, Zinc, Arsenic, Cadmium, Barium, and Lead. The analysis was performed using inductively coupled plasma mass spectrometry, revealing notable concentrations of Pb, Ni, Cd, and Zn, with average levels of 6.85, 156.77, 0.41, and 3.37 mg/kg, respectively. Assessment of target hazard quotients for Pb, against recommended benchmark doses of