Environmental determinants and demographic influences on global urban microbiomes, antimicrobial resistance and pathogenicity.

ABSTRACT: Urban microbiome plays crucial roles in human health and are related to various diseases. The MetaSUB Consortium has conducted the most comprehensive global survey of urban microbiomes to date, profiling microbial taxa/functional genes across 60 cities worldwide. However, the influence of environmental/demographic factors on urban microbiome remains to be elucidated. We collected 35 environmental and demographic characteristics to examine their effects on global urban microbiome diversity/composition by PERMANOVA and regression models. PM₁₀ concentration was the primary determinant factor positively associated with microbial α-diversity (observed species: p = 0.004, β = 1.66, R² = 0.46; Fisher's alpha: p = 0.005, β = 0.68, R² = 0.43), whereas GDP per capita

SUBMITTER: Chen Y 

PROVIDER: S-EPMC10703778 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature