Cortico-muscular connectivity is modulated by passive and active Lokomat-assisted Gait.

ABSTRACT: The effects of robotic-assisted gait (RAG) training, besides conventional therapy, on neuroplasticity mechanisms and cortical integration in locomotion are still uncertain. To advance our knowledge on the matter, we determined the involvement of motor cortical areas in the control of muscle activity in healthy subjects, during RAG with Lokomat, both with maximal guidance force (100 GF-passive RAG) and without guidance force (0 GF-active RAG) as customary in rehabilitation treatments. We applied a novel cortico-muscular connectivity estimation procedure, based on Partial Directed Coherence, to jointly study source localized EEG and EMG activity during rest (standing) and active/passive RAG. We found greater cortico-cortical connectivity, with higher path length and tendency toward segregati

SUBMITTER: Artoni F 

PROVIDER: S-EPMC10703891 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature