The phylogenomic landscape of extended-spectrum β-lactamase producing Citrobacter species isolated from surface water.

ABSTRACT:

Background

Citrobacter species are Gram-negative opportunistic pathogens commonly reported in nosocomial-acquired infections. This study characterised four Citrobacter species that were isolated from surface water in the North West Province, South Africa.

Results

Phenotypic antimicrobial susceptibility profiles of the isolates demonstrated their ability to produce the extended-spectrum β-lactamase (ESBL). Whole genomes were sequenced to profile antibiotic resistance and virulence genes, as well as mobile genetic elements. In silico taxonomic identification was conducted by using multi-locus sequence typing and average nucleotide identity. A pangenome was used to determine the phylogenomic landscape of the Citrobacter species by using 109 publicly available genomes. The strai

SUBMITTER: Chenhaka LH 

PROVIDER: S-EPMC10704729 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature