Cyclic strain of poly (methyl methacrylate) surfaces triggered the pathogenicity of Candida albicans.

ABSTRACT: Candida albicans is an opportunistic yeast and the primary etiological factor in oral candidiasis and denture stomatitis. The pathogenesis of C. albicans could be triggered by several variables, including environmental, nutritional, and biomaterial surface cues. Specifically, biomaterial interactions are driven by different surface properties, including wettability, stiffness, and roughness. Dental biomaterials experience repetitive (cyclic) stresses from chewing and biomechanical movements. Pathogenic biofilms are formed over these biomaterial surfaces under cyclic strain. This study investigated the effect of the cyclic strain (deformation) of biomaterial surfaces on the virulence of Candida albicans. Candida biofilms were grown over Poly (methyl methacrylate) (PMMA) surfaces subjected t

SUBMITTER: Montoya C 

PROVIDER: S-EPMC10705016 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature