Engagement for Alcohol Escalates in the 5-Choice Serial Reaction Time Task After Intermittent Access.

ABSTRACT: Uncontrollable binge drinking is becoming an increasingly prevalent issue in our society. This is a factor that plays a role in the development of alcohol use disorder (AUD). AUD impacts 15 million Americans annually, with approximately 88,000 dying from alcohol related deaths. There are several aspects of AUD that encourage a strong dependence on alcohol. Impulsivity, motivation, and attention are the primary behavioral facets we contribute to AUD. Many past studies have used the 5-Choice Serial Reaction Time Task (5-Choice) to analyze these types of behaviors using sugar as the reward. We have recently published a study where alcohol was used as a reward in the 5-Choice. 48 mice were trained to respond for alcohol in the 5-Choice, and the analyses for these animals were originally catego

SUBMITTER: Starski P 

PROVIDER: S-EPMC10705492 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature