Ontology highlight
ABSTRACT:
SUBMITTER: Gwin CM
PROVIDER: S-EPMC10705497 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Gwin Celena M CM Gupta Kuldeepkumar R KR Lu Yao Y Shao Lin L Rego E Hesper EH
bioRxiv : the preprint server for biology 20231202
Individual cells within clonal populations of mycobacteria vary in size, growth rate, and antibiotic susceptibility. Heterogeneity is, in part, determined by LamA, a protein found exclusively in mycobacteria. LamA localizes to sites of new cell wall synthesis where it recruits proteins important for polar growth and establishing asymmetry. Here, we report that in addition to this function, LamA interacts with complexes involved in oxidative phosphorylation (OXPHOS) at a subcellular location dist ...[more]