Interactive visualization of whole eukaryote genome alignments using NCBI's Comparative Genome Viewer (CGV).

ABSTRACT: We report a new visualization tool for analysis of whole genome assembly-assembly alignments, the Comparative Genome Viewer (CGV) (https://ncbi.nlm.nih.gov/genome/cgv/). CGV visualizes pairwise same-species and cross-species alignments provided by NCBI using assembly alignment algorithms developed by us and others. Researchers can examine the alignments between the two assemblies using two alternate views: a chromosome ideogram-based view or a 2D genome dotplot. Whole genome alignment views expose large structural differences spanning chromosomes, such as inversions or translocations. Users can also navigate to regions of interest, where they can detect and analyze smaller-scale deletions and rearrangements within specific chromosome or gene regions. RefSeq or user-provided gene annotation

SUBMITTER: Rangwala SH 

PROVIDER: S-EPMC10705539 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature