Ontology highlight
ABSTRACT:
SUBMITTER: Yoshida M
PROVIDER: S-EPMC10706978 | biostudies-literature | 2023 Nov
REPOSITORIES: biostudies-literature
Yoshida Maria M Nakashima Ayumu A Ishiuchi Naoki N Miyasako Kisho K Morimoto Keisuke K Tanaka Yoshiki Y Sasaki Kensuke K Maeda Satoshi S Masaki Takao T
International journal of molecular sciences 20231129 23
Mesenchymal stem cells (MSCs) have attracted a great deal of interest as a therapeutic tool for renal fibrosis. Although both adipose-derived and bone marrow-derived MSCs (ADSCs and BMSCs, respectively) suppress renal fibrosis, which of these two has a stronger therapeutic effect remains unclear. This study aimed to compare the antifibrotic effects of ADSCs and BMSCs extracted from adipose tissue and bone marrow derived from the same rats. When cultured in serum-containing medium, ADSCs had a mo ...[more]