Koninginins X-Z, Three New Polyketides from Trichoderma koningiopsis SC-5.

ABSTRACT: Koninginins X-Z (1-3), three novel polyketides, were isolated from the solid fermentation of the endophytic fungus Trichoderma koningiopsis SC-5. Their structures, including the absolute configurations, were comprehensively characterized by a combination of NMR spectroscopic methods, HRESIMS, ¹³C NMR, DFT GIAO ¹³C NMR, and electronic circular dichroism calculations as well as single crystal X-ray diffraction. In addition, all the compounds were evaluated for antifungal activity against Candida albicans.

SUBMITTER: Peng W 

PROVIDER: S-EPMC10707852 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature