Estimating birthweight reduction attributable to maternal ozone exposure in low- and middle-income countries.

ABSTRACT: The effect of O₃ on birthweight in low- and middle-income countries (LMICs) remains unknown. A multicenter epidemiological study was conducted to evaluate the association between maternal peak-season O₃ exposure and birthweight, using 697,148 singleton newborns obtained in 54 LMICs between 2003 and 2019. We estimated the birthweight reduction attributable to peak-season O₃ exposure in 123 LMICs based on a nonlinear exposure-response function (ERF). With every 10-part per billion increment in O₃ concentration, we found a reduction in birthweight of 19.9 g [95% confidence interval (CI): 14.8 to 24.9 g]. The nonlinear ERF had a monotonic decreasing curve, and no safe O₃ exposure threshold was identified. The mean reduction in birthweight

SUBMITTER: Tong M 

PROVIDER: S-EPMC10708175 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature