Diversity of symptom phenotypes in SARS-CoV-2 community infections observed in multiple large datasets.

ABSTRACT: Variability in case severity and in the range of symptoms experienced has been apparent from the earliest months of the COVID-19 pandemic. From a clinical perspective, symptom variability might indicate various routes/mechanisms by which infection leads to disease, with different routes requiring potentially different treatment approaches. For public health and control of transmission, symptoms in community cases were the prompt upon which action such as PCR testing and isolation was taken. However, interpreting symptoms presents challenges, for instance, in balancing the sensitivity and specificity of individual symptoms with the need to maximise case finding, whilst managing demand for limited resources such as testing. For both clinical and transmission control reasons, we require an ap

SUBMITTER: Fyles M 

PROVIDER: S-EPMC10709437 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature